Research at CALA will be mainly directed at biomedical imaging with laser-driven intense X-rays and tumour therapy with laser-produced proton and carbon ion beams. This research will be based on the development achieved in the groups of S. Karsch, F. Grüner, and J. Schreiber. While these groups currently start their activities in the LEX Photonics building, they will finally be located at CALA after its completion. Similarly, the group of F. Pfeiffer will start initial development and research on the Munich Compact Light Source MuCLS in the close-by Munich School of BioEngineering (IMETUM). The CALA research programme will also include the investigation of light-matter interactions at intensities hitherto not attained experimentally, for which theory predicts new types of phenomena.